2rd0

Disease
Known disease associated with this structure: Breast cancer, somatic OMIM:[171834], Colorectal cancer, somatic OMIM:[171834], Gastric cancer, somatic OMIM:[171834], Hepatocellular carcinoma, somatic OMIM:[171834], Nonsmall cell lung cancer, somatic OMIM:[171834], Ovarian cancer, somatic OMIM:[171834]

About this Structure
2RD0 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Figures From The Publication


iSH2 (chain B) , Negative , Positive. Asp, Glu sidechain oxygens , Lys, Arg terminal sidechain nitrogens. No sidechains lack coordinates in this model. As Printed
 * Figure 1B
 * Figure 1C (Labeled)
 * Fig. 1C Spacefilled (Labeled)
 * Figure 2A
 * Figure 2C
 * Figure 2C (Distant portions hidden)
 * Figure 2C (Showing distances)
 * (Figure 2D requires a model containing the nSH2 domain, not present in the published model 2rd0. )
 * Re: Figure 3 -- Surface Charges :
 * Figure 2E: Overview/Location ,

The following residues are missing in the model (lack coordinates):
 * Chain A: 1-7, 307-324, 415-423, 506-527, 941-950. The last modeled residue is 1050.
 * Chain B: 1-441, 510-520, 584-592. The last modeled residue is 600.

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